Training is Medicine; Endurance and Strength Training in Coronary Artery Disease and Health
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High aerobic intensity interval training at 90-95% of maximal heart rate is more effective than continuous training with low to moderate intensity in improving maximal oxygen uptake in healthy young men. Maximal cardiac stroke volume was improved to a similar extent in high aerobic intensity interval training only. It is concluded that high aerobic intensity endurance training is significantly more effective than isocaloric training at lactate threshold (85% of maximal heart rate) or 70% of maximal heart rate, in improving maximal oxygen uptake and cardiac stroke volume. Improvements in maximal oxygen uptake corresponded with changes in stroke volume, indicating a close link between the two. High aerobic intensity interval training at 85-95% of peak heart rate significantly improves peak cardiac stroke volume and resting left ventricular ejection fraction in coronary artery disease patients. High aerobic intensity interval training improves peak cardiac stroke volume and left ventricular ejection fraction in coronary artery disease patients due to increased myocardial contractility and enhanced left ventricular systolic performance. Hyperoxic high aerobic intensity interval training at 85-95% of peak heart rate gave no additional effect over normoxic high aerobic intensity interval training in coronary artery disease patients. Hyperoxic training improves VO2peak and peak stroke volume to the same extent as ambient air training in stable coronary artery disease patients with mild to moderate coronary ischemia. As acute hyperoxia did not increase VO2peak it is concluded that the coronary artery disease patients showed peripheral oxygen limitations in VO2peak both before and after 10 weeks of hyperoxic training. Hyperoxic training may thereby represent no increase in cardiovascular shear stress. Maximal leg press exercise focusing on few repetitions with heavy loads and maximal concentric contractions improves maximal strength, rate of force developments and walking mechanical efficiency in coronary artery disease patients through a minimal exercise effort. Improved muscular strength and rate of force development translates into improved walking mechanical efficiency returning the patients work efficiency to the levels of healthy age matched subjects.
Has partsHelgerud, Jan; Høydal, Kjetil; Wang, Eivind; Karlsen, Trine; Berg, Pål R; Bjerkaas, Marius; Simonsen, Thomas; Helgesen, Cecilie S; Hjorth, Nina L; Bach, Ragnhild; Hoff, Jan. Aerobic High-Intensity Intervals Improve VO2max more than moderate training. Medicine in Science in Sports and Exercise. 39(4): 665-671, 2007.
Helgerud, Jan; Karlsen, Trine; Kim, W Yong; Høydal, Kjetil. How to Improve Stroke Volume in Heart Patients. .
Karlsen, Trine; Hoff, Jan; Støylen, Asbjørn; Skovholdt, Mie Cappelen; Aarhus, Kari Gulbrandsen; Helgerud, Jan. Aerobic interval training improves VO2peak in coronary artery disease patients; no additional effect from hyperoxia. Scandinavian Cardiovascular Journal. 42(5): 303-309, 2008.
PublisherDet medisinske fakultet
SeriesDoktoravhandlinger ved NTNU, 1503-8181; 2008:194
Dissertations at the Faculty of Medicine, 0805-7680; 363