Effects of a multi-component camp-based intervention on inflammatory markers and adipokines in children: A randomized controlled trial
Journal article, Peer reviewed
MetadataShow full item record
- Artikler / Articles 
Original versionPreventive Medicine. 2015, 81, 367-372. http://dx.doi.org/10.1016/j.ypmed.2015.09.014
Objective: To examine the effects of a multi-component overweight intervention on inflammatory markers and adipokines in children. Methods: One hundred and fifteen children were recruited in Odense, Denmark (2011-2014). The participants were randomly allocated to either the day camp intervention arm (DCIA) or the standard intervention arm (SIA). The intervention for the DCIA comprised a 6-week camp intervention and a 46-week family-based intervention. The SIA was offered one weekly physical activity session for 6 weeks and one educational meeting. C-reactive protein (CRP), monocyte chemoattractant protein-1 (MCP1), leptin, and adiponectin were measured in serum at baseline, 6 weeks and 52 weeks. Results: Compared with the SIA, the reductions in CRP (P=0.003) and leptin (p<0.001) were larger in the DCIA at 6 weeks. The intervention effects on leptin were significantly mediated by the changes in body fat mass. No intervention effects on CRP and leptin were seen at 52 weeks. No between-group differences in changes in MCP1 and adiponectin were observed at 6 weeks or 52 weeks. Conclusions: The 6-week camp intervention resulted in reductions in CRP and leptin. The intervention effects did not persist to 52 weeks. The intervention effect on leptin was explained by the changes in body fat mass.
Dette er siste tekst-versjon av artikkelen, og den kan inneholde små forskjeller fra forlagets pdf-versjon. Forlagets pdf-versjon finner du på www.sciencedirect.com / This is the final text version of the article, and it may contain minor differences from the journal's pdf version. The original publication is available at www.sciencedirect.com