A simple synthetic route to methyl 3-fluoropyridine-4-carboxylate by nucleophilic aromatic substitution
Journal article, Peer reviewed
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Original versionMolecules 2006, 11:130-133 10.3390/11020130
The nitro group of methyl 3-nitropyridine-4-carboxylate (1) has successfully been replaced by fluoride anion via nucleophilic aromatic substitution to give the 3-fluoropyridine- 4-carboxylate 2.