Recent Submissions

  • Microfracture is more cost-effective than autologous chondrocyte implantation: a review of level 1 and level 2 studies with 5 year follow-up 

    Aae, Tommy Frøseth; Randsborg, Per-Henrik; Lurås, Hilde; Årøen, Asbjørn; Lian, Øystein Bjerkestrand (Journal article; Peer reviewed, 2017)
    Purpose Focal cartilage defects in the knee may have devastating effect on the knee joint, where two of the main surgical treatment options are microfracture and autologous chondrocyte implantation. Comparative studies ...
  • Quantitative texture analysis in the prediction of IDH status in low-grade gliomas 

    Jakola, Asgeir Store; Zang, YH; Skjulsvik, Anne Jarstein; Solheim, Ole; Bø, Hans Kristian; Berntsen, Erik Magnus; Reinertsen, Ingerid; Gulati, Sasha; Förander, Petter; Brismar, Torkel B. (Journal article; Peer reviewed, 2017)
    Objectives Molecular markers provide valuable information about treatment response and prognosis in patients with low-grade gliomas (LGG). In order to make this important information available prior to surgery the aim of ...
  • Reference ranges for antiepileptic drugs revisited: a practical approach to establish national guidelines 

    Reimers, Arne; Berg, Jon Andsnes; Burns, Margrete Larsen; Brodtkorb, Eylert; Johannessen, Svein Ivar; Landmark, Cecilie Johannessen (Journal article; Peer reviewed, 2018)
    Background and objective: Laboratories sometimes use different reference ranges for the same antiepileptic drug (AED), particularly for new and poorly investigated drugs. This may contribute to misunderstandings, concerns ...
  • Bruk av avansert behandling ved Parkinsons sykdom i Norge / Use of advanced therapies for Parkinson’s disease in Norway 

    Ezat, Beriwan; Pihlstrøm, Lasse; Aasly, Jan; Tysnes, Ole-Bjørn; Egge, Arild; Dietrichs, Espen (Journal article; Peer reviewed, 2017)
    BACKGROUND Many patients with Parkinson’s disease with severe motor fluctuations benefit from advanced therapies – either deep brain stimulation or continuous infusion therapy with levodopa-carbidopa intestinal gel or ...
  • Trondheim Early Neurological Deterioration study Detection and predictors of Early Neurological Deterioration after ischemic stroke 

    Helleberg, Bernt Harald (Doctoral theses at NTNU;2018:48, Doctoral thesis, 2018)
    In 2015, 11000 patients were treated in Norwegian hospitals with stroke as their primary diagnosis. This number may increase substantially over the next decades due to more elderly and very old people in the population. ...
  • Novel genetic loci associated with hippocampal volume 

    Hibar, Derrek; Adams, Hieab H.H.; Jahanshad, Neda; Chauhan, Ganesh; Stein, Jason L.; Hofer, Edith; Renteriá, Miguel E.; Bis, Joshua C.; Arias-Vasquez, Alejandro; Ikram, M. Kamran; Desrivières, Sylvane; Vernooij, Meike W; Abramovic, Lucija; Alhusaini, Saud; Amin, Najaf; Andersson, Micael; Arfanakis, Konstantinos; Aribisala, Benjamin S.; Armstrong, Nicola J.; Athanasiu, Lavinia; Axelsson, Tomas; Beecham, Ashley H.; Beiser, Alexa; Bernard, Manon; Blanton, Susan H.; Bohlken, Marc M.; Boks, Marco P.; Bralten, Janita; Brickman, Adam M.; Carmichael, Owen; Chakravarty, M. Mallar; Chen, Qiang; Ching, Christopher R.K.; Chouraki, Vincent; Cuellar-Partida, Gabriel; Crivello, Fabrice; Den Braber, Anouk; Doan, Nhat Trung; Ehrlich, Stefan; Giddaluru, Sudheer; Goldman, Aaron L; Gottesman, Rebecca F.; Grimm, Oliver; Griswold, Michael E.; Guadalupe, Tulio; Gutman, Boris A.; Hass, Johanna; Haukvik, Unn Kristin H.; Hoehn, David; Holmes, Avram J.; Hoogman, Martine; Janowitz, Deborah; Jia, Tianye; Jørgensen, Kjetil Nordbø; Karbalai, Nazanin; Kasperaviciute, Dalia; Kim, Sungeun; Klein, Marieke; Kraemer, Bernd; Lee, Phil H.; Liewald, David C.M.; Lopez, Lorna M.; Luciano, Michelle; MacAre, Christine; Marquand, André F.; Matarin, Mar; Mather, Karen A.; Mattheisen, Manuel; McKay, David R.; Milaneschi, Yuri; Muñoz Maniega, Susana; Nho, Kwangsik; Nugent, Allison C.; Nyquist, Paul; Loohuis, Loes M. Olde; Oosterlaan, Jaap; Papmeyer, Martina; Pirpamer, Lukas; Pütz, Benno; Ramasamy, Adaikalavan; Richards, Jennifer S.; Risacher, Shannon L.; Roiz-Santiañez, Roberto; Rommelse, Nanda; Ropele, Stefan; Rose, Emma J.; Royle, Natalie A.; Rundek, Tatjana; Sämann, Philipp G.; Saremi, Arvin; Satizabal, Claudia L.; Schmaal, Lianne; Schork, Andrew J.; Shen, Li; Shin, Jean; Shumskaya, Elena; Smith, Albert V.; Sprooten, Emma; Strike, Lachlan T.; Teumer, Alexander; Tordesillas-Gutierrez, Diana; Toro, Roberto; Trabzuni, Daniah; Trompet, Stella; Vaidya, Dhananjay; Van Der Grond, Jeroen; Van Der Lee, Sven J.; Van Der Meer, Dennis; van Donkelaar, Marjolein M.J.; Van Eijk, Kristel R.; Van Erp, Theo G.M.; Van Rooij, Daan; Walton, Esther; Westlye, Lars Tjelta; Whelan, Christopher D.; Windham, Beverly G.; Winkler, Anderson M.; Wittfeld, Katharina; Woldehawariat, Girma; Wolf, Christiane; Wolfers, Thomas; Yanek, Lisa R.; Yang, Jingyun; Zijdenbos, Alex; Zwiers, Marcel P.; Agartz, Ingrid; Almasy, Laura; Ames, David; Amouyel, Philippe; Andreassen, Ole Andreas; Arepalli, Sampath; Assareh, Amelia A.; Barral, Sandra; Bastin, Mark E.; Becker, Diane M.; Becker, James T.; Bennett, David A.; Blangero, John; Van Bokhoven, Hans; Boomsma, Dorret I.; Brodaty, Henry; Brouwer, Rachel M.; Brunner, Han G.; Buckner, Randy L.; Buitelaar, Jan K.; Bulayeva, Kazima B.; Cahn, Wiepke; Calhoun, Vince D.; Cannon, Dara M.; Cavalleri, Gianpiero L.; Cheng, Ching-Yu; Cichon, Sven; Cookson, Mark R.; Corvin, Aiden; Crespo-Facorro, Benedicto; Curran, Joanne E.; Czisch, Michael; Dale, Anders; Davies, Gareth E.; de Craen, Anton J.M.; de Geus, Eco J.C.; De Jager, Philip L.; de Zubicaray, Greig I.; Deary, Ian J.; Debette, Stéphanie; Decarli, Charles; Delanty, Norman; Depondt, Chantal; Destefano, Anita; Dillman, Allissa; Djurovic, Srdjan; Donohoe, Gary; Drevets, Wayne C.; Duggirala, Ravi; Dyer, Thomas D.; Enzinger, Christian; Erk, Susanne; Espeseth, Thomas; Fedko, Iryna O.; Fernandéz, Guillén; Ferrucci, Luigi; Fisher, Simon E.; Fleischman, Debra A.; Ford, Ian; Fornage, Myriam; Foroud, Tatiana M.; Fox, Peter T.; Francks, Clyde; Fukunaga, Masaki; Gibbs, J. Raphael; Glahn, David C.; Gollub, Randy L.; Göring, Harald H.H.; Green, Robert C.; Gruber, Oliver; Gudnason, Vilmundur; Guelfi, Sebastian; Håberg, Asta; Hansell, Narelle K.; Hardy, John; Hartman, Catharina A.; Hashimoto, Ryota; Hegenscheid, Katrin; Heinz, Andreas; Le Hellard, Stephanie; Hernandez, Dena G.; Heslenfeld, Dirk J.; Ho, Beng-Choon; Hoekstra, Pieter J.; Hoffmann, Wolfgang; Hofman, Albert; Holsboer, Florian; Homuth, Georg; Hosten, Norbert; Hottenga, Jouke-Jan; Huentelman, Matthew; Pol, Hilleke E. Hulshoff; Ikeda, Masashi; Jack, Clifford R.; Jenkinson, Mark; Johnson, Robert; Jönsson, Erik Gunnar; Jukema, J. Wouter; Kahn, René S.; Kanai, Ryota; Kloszewska, Iwona; Knopman, David S.; Kochunov, Peter; Kwok, John B.; Lawrie, Stephen M.; Lemaître, Hervé; Liu, Xinmin; Longo, Dan L.; Lopez, Oscar L.; Lovestone, Simon; Martinez, Oliver; Martinot, Jean-Luc; Mattay, Venkata S.; McDonald, Colm; McIntosh, Andrew M.; McMahon, Francis J.; McMahon, Katie L.; Mecocci, Patrizia; Melle, Ingrid; Meyer-Lindenberg, Andreas; Mohnke, Sebastian; Montgomery, Grant W.; Morris, Derek W.; Mosley, Thomas H.; Mühleisen, Thomas W.; Müller-Myhsok, Bertram; Nalls, Michael A.; Nauck, Matthias; Nichols, Thomas E.; Niessen, Wiro J.; Nöthen, Markus M.; Nyberg, Lars; Ohi, Kazutaka; Olvera, Rene L.; Ophoff, Roel A.; Pandolfo, Massimo; Paus, Tomas; Pausova, Zdenka; Penninx, Brenda W.J.H.; Pike, G. Bruce; Potkin, Steven G.; Psaty, Bruce M.; Reppermund, Simone; Rietschel, Marcella; Roffman, Joshua L.; Romanczuk-Seiferth, Nina; Rotter, Jerome I.; Ryten, Mina; Sacco, Ralph L.; Sachdev, Perminder S.; Saykin, Andrew J.; Schmidt, Reinhold; Schmidt, Helena; Schofield, Peter R.; Sigursson, Sigurdur; Simmons, Andrew; Singleton, Andrew; Sisodiya, Sanjay M.; Smith, Colin; Smoller, Jordan W.; Soininen, Hilkka; Steen, Vidar Martin; Stott, David J.; Sussmann, Jessika E; Thalamuthu, Anbupalam; Toga, Arthur W.; Traynor, Bryan J.; Troncoso, Juan; Tsolaki, Magda; Tzourio, Christophe; Uitterlinden, André G.; Hernández, Maria C. Valdés; Van Der Brug, Marcel; Van Der Lugt, Aad; Van Der Wee, Nic J.A.; van Haren, Neeltje E.M.; Van 'T Ent, Dennis; Van Tol, Marie-Jose; Vardarajan, Badri N.; Vellas, Bruno; Veltman, Dick J.; Völzke, Henry; Walter, Henrik; Wardlaw, Joanna M.; Wassink, Thomas H.; Weale, Michael E.; Weinberger, Daniel R.; Weiner, Michael W.; Wen, Wei; Westman, Eric; White, Tonya; Wong, Tien Y.; Wright, Clinton B.; Zielke, Ronald H.; Zonderman, Alan B.; Martin, Nicholas G.; Van Duijn, Cornelia M.; Wright, Margaret J.; Longstreth, William T.; Schumann, Gunter; Grabe, Hans J.; Franke, Barbara; Launer, Lenore J.; Medland, Sarah E.; Seshadri, Sudha; Thompson, Paul M.; Ikram, M. Arfan (Journal article; Peer reviewed, 2017)
    The hippocampal formation is a brain structure integrally involved in episodic memory, spatial navigation, cognition and stress responsiveness. Structural abnormalities in hippocampal volume and shape are found in several ...
  • Collaboration in aphasia rehabilitation The perspective of speech-language pathologists and persons with stroke-induced aphasia 

    Berg, Karianne (Doctoral theses at NTNU;2018:54, Doctoral thesis, 2018)
    Stroke is a major cause of death worldwide, and a seriously disabling health condition often resulting in a persistent need for rehabilitation. New estimates show that there are between 11,000 and 12,000 people suffering ...
  • Genetics and Molecular Pathways in Parkinson's disease and Parkinsonism 

    Gustavsson, Karl Emil (Doctoral theses at NTNU;2018:36, Doctoral thesis, 2018)
    In this thesis I used a wide range of genetic methodologies and biological strategies to unravel the genetic bases of parkinsonian disorders and their clinical relevance. First, in Paper I, we present the discovery of a ...
  • Neuropsychological functioning in a national cohort of severe traumatic brain injury: demographic and acute injury-related predictors 

    Sigurdardottir, Solrun; Andelic, Nada; Wehling, Eike; Røe, Cecilie; Anke, Audny; Skandsen, Toril; Holthe, Øyvor; Jerstad, Tone; Aslaksen, Per Matti; Schanke, Anne-Kristine (Journal article; Peer reviewed, 2015)
    Objectives: To determine the rates of cognitive impairment 1 year after severe traumatic brain injury (TBI) and to examine the influence of demographic, injury severity, rehabilitation, and subacute functional outcomes on ...
  • Primary headache disorders in the adult general population of Pakistan - a cross sectional nationwide prevalence survey 

    Herekar, AA; Ahmad, A; Uqaili, UL; Ahmed, B; Effendi, J; Alvi, SZ; Shahab, MA; Javed, U; Herekar, AD; Khanani, Rafiq; Steiner, Timothy J. (Journal article; Peer reviewed, 2017)
    Background The large geographical gaps in our knowledge of the prevalence and burden of headache disorders include almost all of Eastern Mediterranean Region (EMR). We report a nationwide population-based study in Pakistan, ...
  • Mortality and readmission following hip fracture surgery: A retrospective study comparing conventional and fast-track care 

    Haugan, Kristin; Johnsen, Lars Gunnar; Basso, Trude; Foss, Olav A. (Journal article; Peer reviewed, 2017)
    Objective To compare the efficacies of two pathways—conventional and fast-track care—in patients with hip fracture. Design Retrospective single-centre study. Setting University hospital in middle Norway. Participants ...
  • Epigenetic modulation of stem cells in neurodevelopment: The role of methylation and acetylation 

    Podobinska, Martyna; Szablowska-Gadomska, Ilona; Augustyniak, Justyna; Sandvig, Ioanna; Sandvig, Axel; Buzanska, Leonora (Journal article; Peer reviewed, 2017)
    The coordinated development of the nervous system requires fidelity in the expression of specific genes determining the different neural cell phenotypes. Stem cell fate decisions during neurodevelopment are strictly ...
  • Fatigue and cognition: Pupillary responses to problem-solving in early multiple sclerosis patients 

    de Rodez Benavent, Sigrid Aune; Nygaard, Gro Owren; Harbo, Hanne; Tønnesen, Siren; Sowa, Piotr; Landrø, Nils Inge; Gustavsen, Marte Wendel; Etholm, Lars; Nilsen, Kristian Bernhard; Drolsum, Liv; Kerty, Emilia; Celius, Elisabeth Gulowsen; Laeng, Bruno (Journal article; Peer reviewed, 2017)
    Introduction In early multiple sclerosis (MS) patients, cognitive changes and fatigue are frequent and troublesome symptoms, probably related to both structural and functional brain changes. Whether there is a common ...
  • Occupational and leisure-time physical activity and risk of disability pension: prospective data from the HUNT Study, Norway 

    Fimland, Marius Steiro; Vie, Gunnhild Åberge; Holtermann, Andreas; Krokstad, Steinar; Nilsen, Tom Ivar Lund (Journal article; Peer reviewed, 2017)
    Objectives To prospectively investigate the association between occupational physical activity (OPA) and disability pension due to musculoskeletal cause, mental cause or any cause. We also examined the combined association ...
  • White matter alterations and their associations with motor function in young adults born preterm with very low birth weight. 

    Hollund, Ingrid Marie Husby; Olsen, Alexander; Skranes, Jon Sverre; Brubakk, Ann-Mari; Håberg, Asta; Eikenes, Live; Evensen, Kari Anne Indredavik (Journal article; Peer reviewed, 2017)
    Very low birth weight (VLBW: ≤ 1500 g) individuals have an increased risk of white matter alterations and neurodevelopmental problems, including fine and gross motor problems. In this hospital-based follow-up study, the ...
  • Suboptimal Weight Loss and Weight Regain after Gastric Bypass Surgery - Postoperative Status of Energy Intake, Eating Behavior, Physical Activity, and Psychometrics 

    Amundsen, Tina; Strømmen, Magnus; Martins, Catia (Journal article; Peer reviewed, 2017)
    BACKGROUND: Suboptimal weight loss (SWL) and weight regain (WR) after gastric bypass surgery (GB) remains poorly understood. OBJECTIVES: This study aims to compare GB patients experiencing SWL or significant WR (SigWR) ...
  • Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016 

    Vos, Theo; Abajobir, Amanuel Alemu; Abbafati, Cristiana; Abbas, Kaja M.; Abate, Kalkidan Hassen; Abd-Allah, Foad; Abdulle, Abdishakur M.; Abebo, Teshome Abuka; Abera, Semaw Ferede; Aboyans, Victor; Abu-Raddad, Laith J.; Ackerman, Ilana N.; Adamu, Abdu Abdullahi; Adetokunboh, Olatunji; Afarideh, Mohsen; Afshin, Ashkan; Agarwal, Sanjay Kumar; Aggarwal, Rakesh; Agrawal, Anurag; Agrawal, Sutapa; Kiadaliri, Aliasghar Ahmad; Ahmadieh, Hamid; Ahmed, Muktar Beshir; Aichour, Amani Nidhal; Aichour, Ibtihel; Aichour, Miloud Taki Eddine; Aiyar, Sneha; Akinyemi, Rufus Olusola; Akseer, Nadia; Al Lami, Faris Hasan; Alahdab, Fares; Al-Aly, Ziyad; Alam, Khurshid; Alam, Noore; Alam, Tahiya; Alasfoor, Deena; Alene, Kefyalew Addis; Ali, Raghib; Alizadeh-Navaei, Reza; Alkerwi, Ala'a; Alla, Francois; Allebeck, Peter; Allen, Christine; Al-Maskari, Fatma; Al-Raddadi, Rajaa; Alsharif, Ubai; Alsowaidi, Shirina; Altirkawi, Khalid A.; Amare, Azmeraw T.; Amini, Erfan; Aryal, Krishna Kumar; Htet, Aung Soe; Kisa, Adnan; Knudsen, Ann Kristin; Tollånes, Mette Christophersen; Skirbekk, Vegard Fykse; Steiner, Timothy J.; Stovner, Lars Jacob; Vollset, Stein Emil; Weiderpass, Elisabete (Journal article; Peer reviewed, 2017)
    BACKGROUND: As mortality rates decline, life expectancy increases, and populations age, non-fatal outcomes of diseases and injuries are becoming a larger component of the global burden of disease. The Global Burden of ...
  • Wide awake and surgery 

    Lied, Line; Borchgrevink, Grethe; Finsen, Vilhjalmur (Journal article; Peer reviewed, 2017)
    Background: “Wide awake hand surgery”, where surgery is performed in local anaesthesia with adrenaline, without sedation or a tourniquet, has become widespread in some countries. It has a number of potential advantages and ...
  • Behandling av håndleddsbrudd (distale radiusfrakturer) hos voksne 

    Frønsdal, Katrine Bjørnebek; Kvernmo, Hebe Desiree; Hove, Leiv M; Husby, Torstein; Røkkum, Magne; Odinsson, Adalstein; Skoglund, Knut; Melhuus, Knut; Williksen, John Håkon; Krukhaug, Yngvar; Finsen, Vilhjalmur; Norderhaug, Inger Natvig; Juvet, Lene Kristine; Lauvrak, Vigdis; Fure, Brynjar (Rapport fra Kunnskapssenteret;, Research report, 2013)
  • Characteristics of general movements in preterm infants assessed by computer-based video analysis 

    Adde, Lars; yang, hong; Sæther, Rannei; Jensenius, Alexander Refsum; Ihlen, Espen Alexander F.; Cao, Jia-yan; Støen, Ragnhild (Journal article; Peer reviewed, 2017)
    Background: Previous evidence suggests that the variability of the spatial center of infant movements, calculated by computer-based video analysis software, can identify fidgety general movements (GMs) and predict cerebral ...

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