Recent Submissions

  • Spatiotemporal Distribution of GABAA Receptor Subunits Within Layer II of Mouse Medial Entorhinal Cortex: Implications for Grid Cell Excitability 

    Berggaard, Nina; Seifi, Mohsen; Van der Want, Johannes; Swinny, Jerome (Journal article; Peer reviewed, 2018)
    GABAergic parvalbumin-expressing (PV+) interneurons provide powerful inhibitory modulation of grid cells in layer II of the medial entorhinal cortex (MEC LII). However, the molecular machinery through which PV+ cells ...
  • Development of Parvalbumin-Expressing Basket Terminals in Layer II of the Rat Medial Entorhinal Cortex 

    Berggaard, Nina; Bjerke, Ingvild Elise; Paulsen, Anna Elisabeth Bråthen; Hoang, Linh; Skogaker, Nan Elisabeth Tostrup; Witter, Menno; Van der Want, Johannes (Journal article; Peer reviewed, 2018)
    Grid cells in layer II of the medial entorhinal cortex (MEC LII) generate multiple regular firing fields in response to the position and speed of an individual within the environment. They exhibit a protracted postnatal ...
  • Biochemical profiling of diabetes disease progression by multivariate vibrational microspectroscopy of the pancreas 

    Nord, Christoffer; Eriksson, Maria; Dicker, Andrea; Eriksson, Anna; Grong, Eivind; Ilegems, Erwin; Mårvik, Ronald; Kulseng, Bård Eirik; Berggren, Per-Olof; Gorzsás, András; Ahlgren, Ulf (Journal article; Peer reviewed, 2017)
    Despite the dramatic increase in the prevalence of diabetes, techniques for in situ studies of the underlying pancreatic biochemistry are lacking. Such methods would facilitate obtaining mechanistic understanding of diabetes ...
  • SFRP4 gene expression is increased in aggressive prostate cancer 

    Sandsmark, Elise; Andersen, Maria Karoline; Bofin, Anna M.; Bertilsson, Helena; Drabløs, Finn; Bathen, Tone Frost; Rye, Morten Beck; Tessem, May-Britt (Journal article; Peer reviewed, 2017)
    Increased knowledge of the molecular differences between indolent and aggressive prostate cancer is needed for improved risk stratification and treatment selection. Secreted frizzled-related protein 4 (SFRP4) is a modulator ...
  • Monitoring deep inspiration breath hold for left-sided localized breast cancer radiotherapy with an in-house developed laser distance meter system 

    Jensen, Christer André; Abramova, Tatiana Mikhailovna; Frengen, Jomar; Lund, Jo-Åsmund (Journal article; Peer reviewed, 2017)
    Deep inspiration breath hold (DIBH) in left‐sided breast cancer radiotherapy is a technique to reduce cardiac and pulmonary doses while maintaining target coverage. This study aims at evaluating an in‐house developed DIBH ...
  • Adiponectin prevents orthodontic tooth movement in rats 

    Haugen, Sigrid; Aasarød, Kristin Matre; Stunes, Astrid Kamilla; Mosti, Mats Peder; Franzen, Tanya Jeanette; Vandevska-Radunovic, Vaska; Syversen, Unni; Reseland, Janne Elin (Journal article; Peer reviewed, 2017)
    Objective The objective was to examine the effects of repetitive local administration of adiponectin on experimental tooth movement in rats. Materials and methods The maxillary right first molar of male Wistar rats ...
  • Brain morphometry and cognition in young adults born small for gestational age at term 

    Østgård, Heidi Furre; Løhaugen, Gro; Bjuland, Knut Jørgen; Rimol, Lars Morten; Brubakk, Ann-Mari; Martinussen, Marit; Vik, Torstein; Håberg, Asta; Skranes, Jon Sverre (Journal article; Peer reviewed, 2014)
    Objectives To examine brain volumes and cortical surface area and thickness and to relate these brain measures to cognitive function in young adults born small for gestational age (SGA) at term compared with non-SGA control ...
  • Increased levels of legumain in plasma and plaques from patients with carotid atherosclerosis 

    Lunde, Ngoc Nguyen Dieu; Holm, Sverre; Dahl, Tuva Børresdatter; Inass, Elyouncha; Sporsheim, Bjørnar; Gregersen, Ida; Abbas, Azhar; Skjelland, Mona; Espevik, Terje; Solberg, Rigmor; Johansen, Harald Thidemann; Halvorsen, Bente (Journal article; Peer reviewed, 2017)
    Background and aims The cysteine protease legumain has been shown to be up-regulated in unstable atherosclerotic plaques. This study aims to further elucidate legumain in atherosclerosis, by examining legumain in plasma ...
  • Brain volumes and cognitive function in very-low-birth-weight (VLBW) young adults 

    Bjuland, Knut Jørgen; Rimol, Lars Morten; Løhaugen, Gro; Skranes, Jon Sverre (Journal article; Peer reviewed, 2014)
    Background Preterm born very-low-birth-weight (VLBW: birth weight ≤1500 g) survivors have increased risk of perinatal brain injury that may cause deviant brain development and later neuroimpairments, including reduced ...
  • Whole-body computed tomography versus conventional skeletal survey in patients with multiple myeloma: A study of the International Myeloma Working Group 

    Hillengass, J; Moulopoulos, LA; Delorme, S; Koutoulidis, V; Mosebach, J; Hielscher, T; Drake, M.; Rajkumar, SV; Oestergaard, B; Abildgaard, N; Hinge, M; Plesner, T; Suehara, Y; Matsue, K; Withofs, N; Caers, J; Waage, Anders; Goldschmidt, H; Dimopoulos, MA; Lentzsch, S; Durie, B; Terpos, E (Journal article; Peer reviewed, 2017)
    For decades, conventional skeletal survey (CSS) has been the standard imaging technique for multiple myeloma (MM). However, recently whole-body computed tomography (WBCT) has been implemented into the diagnostic criteria ...
  • Retinopathy of prematurity: Inflammation, choroidal degeneration, and novel promising therapeutic strategies 

    Rivera, Jose Carlos; Holm, Mari; Austeng, Dordi; Morken, Tora Sund; Zhou, Tianwei Ellen; Beaudry-Richard, Alexandra; Sierra, Estefania Marin; Dammann, Olaf; Chemtob, Sylvain (Journal article; Peer reviewed, 2017)
    Retinopathy of prematurity (ROP) is an important cause of childhood blindness globally, and the incidence is rising. The disease is characterized by initial arrested retinal vascularization followed by neovascularization ...
  • Early metabolite changes after melatonin treatment in neonatal rats with hypoxic-ischemic brain injury studied by in-vivo 1H MR spectroscopy 

    Berger, Hester Rijkje; Nyman, Axel Karl Gottfrid; Morken, Tora Sund; Vettukattil, Muhammad Riyas; Brubakk, Ann-Mari; Widerøe, Marius (Journal article; Peer reviewed, 2017)
    Melatonin is a promising neuroprotective agent after perinatal hypoxic-ischemic (HI) brain injury. We used in-vivo 1H magnetic resonance spectroscopy to investigate effects of melatonin treatment on brain metabolism after ...
  • Single cell immune profiling by mass cytometry of newly diagnosed chronic phase chronic myeloid leukemia treated with nilotinib 

    Gullaksen, Stein-Erik; Skavland, Jørn; Gavasso, Sonia; Tosevski, Vinko; Warzocha, Krzysztof; Dumrese, Claudia; Ferrant, Augustin; Gedde-Dahl, Thobias; Hellmann, Andrzej; Janssen, Jeroen; Labar, Boris; Lang, Alois; Majeed, Mohammed Waleed; Mihaylov, Georgi; Stentoft, Jesper; Stenke, Leif; Thaler, Josef; Thielen, Noortje; Verhoef, Gregor; Voglova, Jaroslava; Ossenkoppele, Gert; Hochhaus, Andreas; Hjorth-Hansen, Henrik; Mustjoki, Satu; Sopper, Sieghart; Giles, Francis; Porkka, Kimmo; Wolf, Dominik; Gjertsen, Bjørn Tore (Journal article; Peer reviewed, 2017)
    Monitoring of single cell signal transduction in leukemic cellular subsets has been proposed to provide deeper understanding of disease biology and prognosis, but has so far not been tested in a clinical trial of targeted ...
  • Influenza virus infection, interferon response, viral counter-response, and apoptosis 

    Shim, Jung Min; Kim, Jinhee; Tenson, Tanel; Min, Ji-Young; Kainov, Denis (Journal article; Peer reviewed, 2017)
    Human influenza A viruses (IAVs) cause global pandemics and epidemics, which remain serious threats to public health because of the shortage of effective means of control. To combat the surge of viral outbreaks, new ...
  • Antiviral properties of chemical inhibitors of cellular anti-apoptotic Bcl-2 proteins 

    Bulanova, Daria; Ianevski, Aleksandr; Bugai, Andrii; Akimov, Yevhen; Kuivanen, Suvi; Paavilainen, Henrik; Kakkola, Laura; Nandania, Jatin; Turunen, Laura; Ohman, Tiina; Ala-Hongisto, Hanna; Pesonen, Hanna M; Kuisma, Marika S; Honkimaa, Anni; Walton, Emma Louise; Oksenych, Valentyn; Lorey, Martina B.; Guschin, Dmitry; Shim, Jungmin; Kim, Jinhee; Than, Thoa T; Chang, So Young; Hukkanen, Veijo; Kulesskiy, Evgeny; Marjomaki, Varpu S; Julkunen, Ilkka; Nyman, Tuula Anneli; Matikainen, Sampsa; Saarela, Jani S; Sane, Famara; Hober, Didier; Gabriel, Gulsah; De Brabander, Jef K; Martikainen, Miika; Windisch, Marc P; Min, Ji-Young; Bruzzone, Roberto; Aittokallio, Tero; Vaha-Koskela, Markus; Vapalahti, Olli; Pulk, Arto; Velagapudi, Vidya; Kainov, Denis (Journal article; Peer reviewed, 2017)
    Viral diseases remain serious threats to public health because of the shortage of effective means of control. To combat the surge of viral diseases, new treatments are urgently needed. Here we show that small-molecules, ...
  • Peak bone mass and bone microarchitecture in adults born with low birth weight preterm or at term: A cohort study 

    Balasuriya, Chandima Nirupa Dilruks; Evensen, Kari Anne Indredavik; Mosti, Mats Peder; Brubakk, Ann-Mari; Jacobsen, Geir Wenberg; Indredavik, Marit Sæbø; Schei, Berit; Stunes, Astrid Kamilla; Syversen, Unni (Journal article; Peer reviewed, 2017)
    Context and Objectives: Peak bone mass (PBM) is regarded as the most important determinant of osteoporosis. Growing evidence suggests a role of intrauterine programming in skeletal development. We examined PBM and trabecular ...
  • Change-point analysis data of neonatal diffusion tensor MRI in preterm and term-born infants 

    Wu, Dan; Chang, Linda; Akazawa, Kentaro; Oishi, Kumiko; Skranes, Jon Sverre; Ernst, Thomas; Oishi, Kenichi (Journal article; Peer reviewed, 2017)
    The data presented in this article are related to the research article entitled “Mapping the Critical Gestational Age at Birth that Alters Brain Development in Preterm-born Infants using Multi-Modal MRI” (Wu et al., 2017) ...
  • Investigating the causal effect of smoking on hay fever and asthma: A Mendelian randomization meta-analysis in the CARTA consortium 

    Skaaby, Tea; Taylor, Amy E; Jacobsen, Rikke K.; Paternoster, Lavinia; Thuesen, Betina H.; Ahluwalia, Tarunveer S.; Larsen, Sofus C.; Zhou, Ang; Wong, Andrew; Gabrielsen, Maiken Elvestad; Bjørngaard, Johan Håkon; Flexeder, Claudia; Männistö, Satu; Hardy, Rebecca; Kuh, Diana; Barry, Sarah J.; Møllehave, Line Tang; Cerqueira, Charlotte; Friedrich, Nele; Bonten, Tobias N.; Noordam, Raymond; Mook-Kanamori, Dennis O.; Taube, Christian; Jessen, Leon E.; McConnachie, Alex; Sattar, Naveed; Upton, Mark N.; McSharry, Charles; Bønnelykke, Klaus; Bisgaard, Hans; Schulz, Holger; Strauch, Konstantin; Meitinger, Thomas; Peters, Annette; Grallert, Harald; Nohr, Ellen A.; Kivimäki, Mika; Kumari, Meena; Völker, Uwe; Nauck, Matthias; Völzke, Henry; Power, Chris; Hyppönen, Elina; Hansen, Torben; Jørgensen, Torben; Pedersen, Oluf; Salomaa, Veikko; Grarup, Niels; Langhammer, Arnulf; Romundstad, Pål Richard; Skorpen, Frank; Kaprio, Jaakko; Munafò, Marcus R.; Linneberg, Allan (Journal article; Peer reviewed, 2017)
    Observational studies on smoking and risk of hay fever and asthma have shown inconsistent results. However, observational studies may be biased by confounding and reverse causation. Mendelian randomization uses genetic ...
  • JWA regulates TRAIL-induced apoptosis via MARCH8-mediated DR4 ubiquitination in cisplatin-resistant gastric cancer cells 

    Wang, Q; Chen, Q; Zhu, L; Chen, M; Xu, W; Panday, S; Wang, Z; Li, A; Røe, Oluf Dimitri; Chen, R; Wang, S; Zhang, R; Zhou, J (Journal article; Peer reviewed, 2017)
    Platinum chemotherapeutics are widely used to treat solid malignant tumors, including gastric cancer (GC). Drug resistance to platinum compounds may result in cancer relapse and decreased survival. The identification and ...
  • A systematic review of maternal smoking during pregnancy and fetal measurements with meta-analysis 

    Abraham, Miriam; Alramadhan, Salem; Iñiguez, Carmen; Duijts, Liesbeth; Jaddoe, Vincent W.V.; Den Dekker, Herman T.; Crozier, Sarah; Godfrey, Keith M.; Hindmarsh, Peter; Vik, Torstein; Jacobsen, Geir Wenberg; Hanke, Wojciech; Sobala, Wojciech; Devereux, Graham; Turner, Steve (Journal article; Peer reviewed, 2017)
    Background Maternal smoking during pregnancy is linked to reduced birth weight but the gestation at onset of this relationship is not certain. We present a systematic review of the literature describing associations between ...

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