Nye registreringer

  • Limits to human enhancement: Nature, disease, therapy or betterment? 

    Hofmann, Bjørn (Journal article; Peer reviewed, 2017)
    Background New technologies facilitate the enhancement of a wide range of human dispositions, capacities, or abilities. While it is argued that we need to set limits to human enhancement, it is unclear where we should ...
  • Prevalence and burden of headache disorders in Lithuania and their public-health and policy implications: a population-based study within the Eurolight Project 

    Rastenyte, Daiva; Mickeviciene, Dalia; Stovner, Lars Jacob; Thomas, Hallie; Andrée, Colette; Steiner, Timothy J. (Journal article; Peer reviewed, 2017)
    Background The Eurolight project assessed the impact of headache disorders in ten EU countries, using the same structured questionnaire but varying sampling methods. In Lithuania, sample selection employed methods in line ...
  • Preventing physical abuse of Nursing home residents- as seen from the Nursing staff's perspective 

    Braaten, Kjersti Lisbeth; Malmedal, Wenche Karin (Journal article; Peer reviewed, 2017)
    Aim This study aims to capture first-hand information from nursing home staff's own understanding regarding what they think and have experienced about prevention of physical abuse of nursing home residents and what ...
  • Vitamin D and cognitive function: A Mendelian randomisation study 

    Maddock, Jane; Zhou, Ang; Cavadino, Alana; Kuźma, Elżbieta; Bao, Yanchun; Smart, Melissa C.; Saum, Kai-Uwe; Schöttker, Ben; Engmann, Jorgen; Kjærgaard, Marie; Karhunen, Ville; Zhan, Yiqiang; Lehtimäki, Terho; Rovio, Suvi P.; Byberg, Liisa; Lahti, Jari; Marques-Vidal, Pedro; Sen, Abhijit; Perna, Laura; Schirmer, Henrik; Singh-Manoux, Archana; Auvinen, Juha; Hutri-Kähönen, Nina; Kähönen, Mika; Kilander, Lena; Räikkönen, Katri; Melhus, Håkan; Ingelsson, Erik; Guessous, Idris; Petrovic, Katja E.; Schmidt, Helena; Schmidt, Reinhold; Vollenweider, Peter; Lind, Lars; Eriksson, Johan G.; Michaëlsson, Karl; Raitakari, Olli T; Hägg, Sara; Pedersen, Nancy L.; Herzig, Karl-Heinz; Järvelin, Marjo-Riitta; Veijola, Juha; Kivimäki, Mika; Jorde, Rolf; Brenner, Hermann; Kumari, Meena; Power, Chris; Llewellyn, David J.; Hyppönen, Elina (Journal article; Peer reviewed, 2017)
    The causal nature of the association between hypovitaminosis D and poor cognitive function in mid- to later-life is uncertain. Using a Mendelian randomisation(MR) approach, we examined the causal relationship between 25(OH)D ...
  • Do health professionals have a prototype concept of disease? The answer is no 

    Hofmann, Bjørn (Journal article; Peer reviewed, 2017)
    Background Health and disease are core concepts in health care and have attracted substantial interest and controversy. In recent and interesting contributions to the debate it has been argued that the challenges with ...
  • A multimodal image guiding system for Navigated Ultrasound Bronchoscopy (EBUS): A human feasibility study 

    Sorger, Hanne; Hofstad, Erlend Fagertun; Amundsen, Tore; Langø, Thomas; Bakeng, Janne Beate Lervik; Leira, Håkon Olav (Journal article; Peer reviewed, 2017)
    Background Endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) is the endoscopic method of choice for confirming lung cancer metastasis to mediastinal lymph nodes. Precision is crucial for correct staging ...
  • Polygenic overlap between C-reactive protein, plasma lipids, and Alzheimer disease 

    Desikan, Rahul S.; Schork, Andrew J.; Wang, Yunpeng; Thompson, Wesley K.; Dehghan, Abbas; Ridker, Paul M.; Chasman, Daniel I.; McEvoy, Linda K.; Holland, Dominic; Chen, Chi-Hua; Karow, David S.; Brewer, James B.; Hess, Christopher P.; Williams, Julie; Sims, Rebecca; O'Donovan, Michael C.; Choi, Seung Hoan; Bis, Joshua C.; Ikram, M. Arfan; Gudnason, Vilmundur; DeStefano, Anita L.; Van Der Lee, Sven J.; Psaty, Bruce M.; Van Duijn, Cornelia M.; Launer, Lenore; Seshadri, Sudha; Pericak-Vance, Margaret A.; Mayeux, Richard; Haines, Jonathan L.; Farrer, Lindsay A.; Hardy, John; Ulstein, Ingun; Aarsland, Dag; Fladby, Tormod; White, Linda; Sando, Sigrid Botne; Rongve, Arvid; Witoelar, Aree; Djurovic, Srdjan; Hyman, Bradley T.; Snædal, Jon; Steinberg, Stacy; Stefansson, Hreinn; Stefánsson, Kári; Schellenberg, Gerard D.; Andreassen, Ole Andreas; Dale, Anders (Journal article; Peer reviewed, 2015)
    Background—Epidemiological findings suggest a relationship between Alzheimer disease (AD), inflammation, and dyslipidemia, although the nature of this relationship is not well understood. We investigated whether this ...
  • Wnt5a is associated with right ventricular dysfunction and adverse outcome in dilated cardiomyopathy 

    Abraityte, Judita Aurelija; Lunde, Ida Gjervold; Askevold, Erik Tandberg; Michelsen, Annika; Christensen, Geir Arve; Aukrust, Pål; Yndestad, Arne; Fiane, Arnt E; Andreassen, Arne K.; Aakhus, Svend; Dahl, Christen Peder; Gullestad, Lars; Broch, Kaspar; Ueland, Thor (Journal article; Peer reviewed, 2017)
    The Wingless (Wnt) pathway has been implicated in the pathogenesis of dilated cardiomyopathy (DCM). To explore the role of Wnt modulators Wnt5a and sFRP3 in DCM patients we analyzed the expression of Wnt5a and sFRP3 in ...
  • Metabolomics and Gene Expression Analysis Reveal Down-regulation of the Citric Acid (TCA) Cycle in Non-diabetic CKD Patients 

    Hallan, Stein; Afkarian, Maryam; Zelnick, Leila R.; Kestenbaum, Bryan; Sharma, Shoba; Saito, Rintaro; Darshi, Manjula; Barding, Gregory; Raftery, Daniel; Ju, Wenjun; Kretzler, Matthias; Sharma, Kumar; de Boer, Ian H. (Journal article; Peer reviewed, 2017)
    Chronic kidney disease (CKD) is a public health problem with very high prevalence and mortality. Yet, there is a paucity of effective treatment options, partly due to insufficient knowledge of underlying pathophysiology. ...
  • Interleukin 27 is increased in carotid atherosclerosis and promotes NLRP3 inflammasome activation. 

    Gregersen, Ida; Sandanger, Øystein; Askevold, Erik Tandberg; Sagen, Ellen Lund; Yang, Kuan; Holm, Sverre; Pedersen, Turid Margrethe; Skjelland, Mona; Krohg-Sørensen, Kirsten; Hansen, Trond Vidar; Dahl, Tuva Børresdatter; Otterdal, Kari; Espevik, Terje; Aukrust, Pål; Yndestad, Arne; Halvorsen, Bente (Journal article; Peer reviewed, 2017)
    Aim Interleukin-27 (IL-27) is involved in different inflammatory diseases; however, its role in atherosclerosis is unclear. In this study we investigated the expression of IL-27 and its receptor in patients with carotid ...
  • Productivity growth, case mix and optimal size of hospitals. A 16-year study of the Norwegian hospital sector 

    Anthun, Kjartan Sarheim; Kittelsen, Sverre A.C.; Magnussen, Jon (Journal article, 2017)
    Background and objectives This paper analyses productivity growth in the Norwegian hospital sector over a period of 16 years, 1999–2014. This period was characterized by a large ownership reform with subsequent hospital ...
  • Pattern recognition receptor mediated inflammation in placental trophoblasts 

    Stødle, Guro Sannerud (Doctoral theses at NTNU;2017:324, Doctoral thesis, 2017)
  • Integration of grid maps in merged environments 

    Wernle, Tanja; Waaga, Torgeir; Mørreaunet, Maria; Treves, Alessandro; Moser, May-Britt; Moser, Edvard Ingjald (Journal article; Peer reviewed, 2018)
    Natural environments are represented by local maps of grid cells and place cells that are stitched together. The manner by which transitions between map fragments are generated is unknown. We recorded grid cells while rats ...
  • Heavier smoking increases coffee consumption: findings from a Mendelian randomization analysis 

    Bjørngaard, Johan Håkon; Nordestgaard, AT; Taylor, Amy E; Treur, Jorien L; Gabrielsen, Maiken Elvestad; Munafo, Marcus R; Nordestgaard, BG; Åsvold, Bjørn Olav; Romundstad, Pål Richard; Davey Smith, George (Journal article; Peer reviewed, 2017)
    Background There is evidence for a positive relationship between cigarette and coffee consumption in smokers. Cigarette smoke increases metabolism of caffeine, so this may represent a causal effect of smoking on caffeine ...
  • Cardiovascular mortality ? Comparing risk factor associations within couples and in the total population ? The HUNT Study 

    Bjørngaard, Johan Håkon; Vie, Gunnhild Åberge; Krokstad, Steinar; Janszky, Imre; Romundstad, Pål Richard; Vatten, Lars Johan (Journal article; Peer reviewed, 2017)
    Background To compare associations of conventional risk factors with cardiovascular death within couples and in the population as a whole. Methods We analysed baseline data (1995–97) from the HUNT2 Study in Norway ...
  • Maternal Age at Child Birth, Birth Order, and Suicide at a Young Age: A Sibling Comparison 

    Bjørngaard, Johan Håkon; Bjerkeset, Ottar; Vatten, Lars Johan; Janszky, Imre; Gunnell, David; Romundstad, Pål Richard (Journal article; Peer reviewed, 2013)
    Previous studies have reported strong associations between birth order, maternal age, and suicide, but these results might have been confounded by socioeconomic and other factors. To control for such factors, we compared ...
  • Care pathways as boundary objects between primary and secondary care: Experiences from Norwegian home care services 

    Håland, Erna; Røsstad, Tove; Osmundsen, Tonje (Journal article; Peer reviewed, 2015)
    The need for integration of healthcare services and collaboration across organisational boundaries is highlighted as a major challenge within healthcare in many countries. Care pathways are often presented as a solution ...
  • Effect of a single dose of the interleukin-6 receptor antagonist tocilizumab on inflammation and troponin T release in patients with non-ST-elevation myocardial infarction: a double-blind, randomized, placebo-controlled phase 2 trial 

    Kleveland, Ola; Kunszt, Gabor; Bratlie, Marte; Ueland, Thor; Broch, Kaspar; Holte, Espen; Michelsen, Annika; Bendz, Bjørn; Amundsen, Brage H.; Espevik, Terje; Aakhus, Svend; Damås, Jan Kristian; Aukrust, Pål; Wiseth, Rune; Gullestad, Lars (Journal article; Peer reviewed, 2016)
    Aims Interleukin-6 (IL-6) contributes to atherosclerotic plaque destabilization and is involved in myocardial injury during ischaemia–reperfusion. Interleukin-6 is therefore a potential therapeutic target in myocardial ...
  • A study of human resource competencies required to implement community rehabilitation in less resourced settings 

    Gilmore, Brynne; MacLachlan, Malcolm; McVeigh, Joanne; McClean, Chiedza; Carr, Stuart; Duttine, Antony; Mannan, Hasheem; McAuliffe, Eilish; Mji, Gubela; Eide, Arne Henning; Hem, Karl-Gerhard; Gupta, Neeru (Journal article; Peer reviewed, 2017)
    Background It is estimated that over one billion persons worldwide have some form of disability. However, there is lack of knowledge and prioritisation of how to serve the needs and provide opportunities for people with ...
  • Cytotoxicity of poly(Alkyl cyanoacrylate) nanoparticles 

    Sulheim, Einar; Iversen, Tore Geir; To, Vu; Klinkenberg, Geir; Sletta, Håvard; Schmid, Ruth; Hatletveit, Anne Rein; Wågbø, Ane Marit; Sundan, Anders; Skotland, Tore; Sandvig, Kirsten; Mørch, Ýrr Asbjørg (Journal article; Peer reviewed, 2017)
    Although nanotoxicology has become a large research field, assessment of cytotoxicity is often reduced to analysis of one cell line only. Cytotoxicity of nanoparticles is complex and should, preferentially, be evaluated ...

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