Browsing Institutt for bioteknologi og matvitenskap by Subject "MBIOT5 Bioteknologi (5 årig)"
Now showing items 1-20 of 20
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Analytical Methods for Determination of the Oxidative Status in Oils
(Master thesis, 2012)In industry today standard oxidative quality parameters are based on measurements of primary and secondary oxidation products, measured by PV and AV respectively. These methods are all prone to limitations and weaknesses, ... -
Differentially Regulated pathways of Potential Importance for Treatment Response and Cardiac Toxicity after Administration of Doxorubicine to BC Patients
(Master thesis, 2012)Doxorubicin is a topoisomerase-targeting anthracycline that is one of the most effective anticancer drugs currently known. However, its clinical use is restricted by cardiotoxicity and the development of drug resistance. ... -
Drug Delivery Using Oral Vehicles: Controlled Release in the GI-tract
(Master thesis, 2012)Oral delivery is considered a convenient route for administration of pharmaceuticals. Great effort has been made to optimize oral delivery vehicles to increase the bioavailability of the pharmaceutical, and enhance patient ... -
Extraction and Analysis of Marine Lipids with Emphasis on Phospholipids- Evaluation and Improvement of Methods
(Master thesis, 2011)Extraction and Analysis of Marine Lipids with Emphasis on Phospholipids- Evaluation and Improvement of Methods -
Fiskefarse med redusert innhold av salt (NaCl) og tilsatt natriumalginat
(Master thesis, 2012)Flere studier har vist at saltinntaket til mennesker er for høyt, noe som kan føre til økt risiko for blant annet høyt blodtrykk og hjerte- og karsykdommer. Den største delen av saltinntaket kommer fra mat som er bearbeidet. ... -
Heparin Analogs Created by Sulfation of Alginates Using a Chemoenzymatic Strategy
(Master thesis, 2012)Alginates are a class of natural unbranched linear polysaccharides, and consist of the monomers β-D-mannuronic acid and α-L-guluronic acid. The inherent physical properties, relative ease of modification, wide availability ... -
How the antimicrobial Protein, Lipocalin 2, affects the Establishment of Microbiota in the Gut of Mice.
(Master thesis, 2012)Several studies have suggested that the host genetics may influence the composition of gut microbiota, but few genes involved in host control have been proposed (Sekirov et al., 2010). Lipocalin 2 (Lcn2) prevents growth ... -
Karakterisering av mikrobiota i vill torsk (Gadus morhua)
(Master thesis, 2012)Det har i senere tid vært en økende interesse for GI-mikrobiota i fisk, men det er fremdeles begrenset kunnskap om mikrobiotaens sammensetning og funksjon i tarmen hos vill fisk. Målet med dette prosjektet var å karakterisere ... -
Lavsaltprodukter av fisk: Betydning av ulike salter på egenskapene til muskelproteiner
(Master thesis, 2012)Prosessert mat utgjør en av de største kildene til natrium i vestlig kosthold. Et forhøyet inntak av natrium er forbundet med høyt blodtrykk, noe som øker risikoen for hjerte- og karsykdommer. Denne kunnskapen har økt ... -
Optimalised Carbodiimide Chemistry for RGD-coupled Alginate
(Master thesis, 2012)Alginate is a naturally ocurring polyanion of (1→4)linked β-d-mannuronic acid (M)and its C-5 epimer α-l guluronic acid (G). The polyanion, and particularly longstretches of guluronic acids, chelates and form hydrogels in ... -
Optimzing the 5'-end of Coding Sequences in Recombinant mRNA to achieve high-level Expression in the Bacterium Escherichia coli
(Master thesis, 2012)Recombinant protein production in Escherichia coli provides a cheap and efficient way of producing medically and industrially relevant proteins. Sequence features of individual genes and especially their 5 terminal coding ... -
Particle Mobility in Mucus: Role of Surface Interactions and Use of G-blocks
(Master thesis, 2012)The mucus layers on the internal surfaces of the human body serve as an important barrier against foreign material, but it also create restrictions regarding drug delivery. Discovering methods to overcome this barrier would ... -
Recombinant Gene Expression in Escherichia coli: An Experiment and Literature-Based Study of the Roles of the 5'-Ends of Target Genes
(Master thesis, 2012)Experiment-based study: The 5 -untranslated region (5 -UTR), and the DNA region corresponding to it, have been shown to have a significant influence on the expression of genes both at transcriptional and translational ... -
Rensing og karakterisering av mannuronan C-5-epimeraser produsert rekombinant i Hansenula polymorpha og mutante epimeraser produsert rekombinant i Escherichia coli
(Master thesis, 2012)Alginat er et polysakkarid som kommersielt utvinnes fra algekilder. Anvendelsesområder for alginat er blant annet mat, farmasi og biomedisin. Strukturen til alginat er avhengig av kilden den er ekstrahert fra, og komposisjonen ... -
Study of Rat Olfactory Ensheathing Cells in Alginate based Matrices
(Master thesis, 2012)Alginate hydrogel made from alginate and crosslinking divalent ions is a natural biomaterial that is biocompatible, has low toxicity, is relatively cheap and has mild gelation chemistry. It is a porous material that allows ... -
Superchilling of Salmon (Salmo salar)
(Master thesis, 2013)The aim of this thesis was to study discolorations in superchilled muscle food discovered by Duun (2008) The discolorations was found in salmon, pork and cod, and was not microbiological. The hypothesis as that this is a ... -
The B7-H3 Protein and its role in Breast Cancer Treatment Response
(Master thesis, 2012)Breast cancer is the most common cancer type amongst women, and closer to 3000 women in Norway will be diagnosed with this disease in 2012. Although major improvements have been achieved in the treatment, and thus the ... -
The Expression of microRNAs in Hantavirus Infections
(Master thesis, 2011)Hantaviruses cause serious human diseases, Hemorrhagic fever with renal syndrome (HFRS) and Hantavirus pulmonary syndrome (HPS), depending on the virus type. Currently no vaccine exists and the existing drug therapy for ... -
The Role of Lipocalin 2 in the Shaping of the Gastrointestinal Microbiota and Development of Inflammatory Bowel Disease in Mice
(Master thesis, 2013)The gastrointestinal microbiota have long been associated with health and disease in humans. Inflammatory bowel disease (IBD) is a disease thought to arise from a dysfunctional immune response to the commensal microbiota ... -
Transdermal Delivery of Water Soluble Molecules into Human Skin
(Master thesis, 2012)The skin is the largest organ of the human body and it constitutes a great protective barrier against entry of harmful microbial species and foreign materials into the body. The barrier function is a result of the highly ...