Expired nitric oxide after high intensive exercise at altitude
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Nitric oxide has, as an exhaled biomarker, become an accepted tool in the management of inflammatory airway diseases, with its non-invasive, quick and easy measurement procedures. However, its use is still discussed and NO have currently only been assigned a complementary value. Other studies have reported reduced partial pressure of expired [NO] (PENO) at altitude (Hemmingsson and Linnarsson, 2009) and acute hypoxia is shown to down-regulate NO synthesis (Brown et al., 2006). Exercise alter values of expired NO concentration (FENO) (Shin et al., 2003). A large individual variance of FENO has also been reported in the literature (Olivieri et al., 2006). Different methods (i. e. flow rate) and measurement equipment may account for some of the variety of available research results and materials today. The purpose of this study was to examine changes in and the course of expired [NO] (FENO and PENO) after high intensive exercise, during exposure to reduced barometric pressure.
Masteroppgave – Norges idrettshøgskole, 2010.