• English
    • norsk
  • English 
    • English
    • norsk
  • Login
View Item 
  •   All institutions
  • Norges idrettshøgskole
  • Artikler / Articles
  • View Item
  •   All institutions
  • Norges idrettshøgskole
  • Artikler / Articles
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Waist circumference is related to low-grade inflammation in youth

Steene-Johannessen, Jostein; Kolle, Elin; Reseland, Janne E.; Anderssen, Sigmund A.; Andersen, Lars Bo
Journal article, Peer reviewed
Thumbnail
View/Open
Steene-Johannessen IntJPedObesity 2010.pdf (160.2Kb)
Permanent link
http://hdl.handle.net/11250/170869
Issue date
2010
Share
Metadata
Show full item record
Collections
  • Artikler / Articles [890]
Original version
International Journal of Pediatric Obesity. 2010, 5(4), 313-319  
Abstract
Objectives. To examine markers of infl ammation in 9- and 15-year-olds with high waist circumference and compare these

with controls, and to examine the relationships between infl ammatory markers and cardiovascular disease (CVD) risk factors.

Methods. Cross-sectional analysis of data from 2 299 Norwegian 9- and 15-year-olds participating in the “Physical

activity among Norwegian Children Study”. In each sex and age group, the 10 participants with the highest waist circumference

(HW) were selected (n 40) for analyses, and a random sample of 40 participants within the same groups were

included as controls. Infl ammatory markers included C-reactive protein (CRP), leptin, adiponectin, plasminogen activator

inhibitor-1 (PAI-1), tumor necrosis factor-α (TNF-α), hepatocyte growth factor (HGF), resistin and interleukin-6 (IL-6).

The CVD risk factors included blood pressure, glucose, insulin, triglycerides and high density lipoprotein cholesterol.

Results. HW participants had elevated levels of CRP (mean difference 1.50 mg/l; 95% confi dence interval [CI] 0.33 to 2.66),

PAI-1 (mean difference 13.3 ng/ml; 95% CI 4.1 to 22.5) and HGF (mean difference 0.29 ng/ml; 95% CI 0.07 to 0.51) compared

with controls. All CVD risk factors differed between the HW group and controls. The CVD risk factors were not

associated with TNFα or IL-6, but CRP, HGF and PAI-1 were related to the metabolic risk score. Conclusions. Low grade

systemic infl ammation is already present in youth with high waist circumference. CRP, HGF and PAI-1 may be related to

the adverse overall metabolic risk profi le observed in these children and adolescents.
Description
I Brage finner du siste tekst-versjon av artikkelen, og den kan inneholde ubetydelige forskjeller fra forlagets pdf-versjon. Forlagets pdf-versjon finner du på www.informaworld.com: http://dx.doi.org/10.3109/17477160903497035 / In Brage you'll find the final text version of the article, and it may contain insignificant differences from the journal's pdf version. The original publication is available at www.informaworld.com: http://dx.doi.org/10.3109/17477160903497035
Publisher
Taylor & Francis

Contact Us

Search NORA
Powered by DSpace software

Service from BIBSYS
 

 

Browse this CollectionIssue DateAuthorsTitlesSubjectsDocument TypesJournalsBrowse all ArchivesArchives & CollectionsIssue DateAuthorsTitlesSubjectsDocument TypesJournals

My Account

Login

Statistics

Google Analytics StatisticsView Usage Statistics

Contact Us

Search NORA
Powered by DSpace software

Service from BIBSYS