• A life course study of the relationship between pregnancy and cardiovascular health in women The HUNT study in Norway 

      Haug, Eirin Beate (Doctoral theses at NTNU;2018:406, Doctoral thesis, 2018)
    • Alterations in the Vitamin D endocrine system during pregnancy: A longitudinal study of 855 healthy Norwegian women 

      Gustafsson, Miriam; Romundstad, Pål Richard; Stafne, Signe Nilssen; Helvik, Anne-Sofie; Stunes, Astrid Kamilla; Mørkved, Siv; Salvesen, Kjell Å; Thorsby, Per Medbøe; Syversen, Unni (Journal article; Peer reviewed, 2018)
      To ensure optimal calcium accrual in the fetal skeleton, a substantial rise occurs in 1,25-dihydroxyvitamin D (1,25(OH)2D), but is dependent on sufficient 25-hydroxyvitamin (25(OH)D). Large longitudinal studies addressing ...
    • Association of body mass index with depression, anxiety and suicide - An instrumental variable analysis of the HUNT study 

      Bjørngaard, Johan Håkon; Carslake, David; Nilsen, Tom Ivar Lund; Linthorst, Astrid C E; Smith, George Davey; Gunnell, David; Romundstad, Pål Richard (Journal article, 2015)
      Objective: While high body mass index is associated with an increased risk of depression and anxiety, cumulative evidence indicates that it is a protective factor for suicide. The associations from conventional observational ...
    • Associations between the MDM2 promoter P1 polymorphism del1518 (rs3730485) and incidence of cancer of the breast, lung, colon and prostate 

      Lønning, Per Eystein; Gansmo, Liv Beathe; Romundstad, Pål Richard; Ryan, Bríd M.; Hveem, Kristian; Knappskog, Stian; Harris, Curtis C.; Vatten, Lars Johan (Journal article; Peer reviewed, 2016)
      The MDM2 promoter region contains several polymorphisms, some of which have been associated with MDM2 expression, cancer risk and age at cancer onset. del1518 (rs3730485) is an indel polymorphism residing in the MDM2 ...
    • Associations of serum 25-hydroxyvitamin D level with incidence of lung cancer and histologic types in Norwegian adults: a case-cohort analysis of the HUNT study 

      Sun, Yi-Qian; Langhammer, Arnulf; Wu, Chunsen; Skorpen, Frank; Chen, Yue; Nilsen, Tom Ivar Lund; Romundstad, Pål Richard; Mai, Xiao-Mei (Journal article, 2017)
      Background: Previous prospective studies have shown inconsistent associations between serum 25-hydroxyvitamin D [25(OH)D] level and lung cancer incidence. The aim of the present study was to explore the associations of ...
    • Cancer cachexia associates with a systemic autophagy-inducing activity mimicked by cancer cell-derived IL-6 trans-signaling 

      Pettersen, Kristine; Andersen, Sonja Benedikte; Degen, simone; Tadini, Valentina; Grosjean, Joel; Hatakeyama, Shinji; Tesfahun, Almaz Nigatu; Moestue, Siver Andreas; Kim, Jana; Nonstad, Unni; Romundstad, Pål Richard; Skorpen, Frank; Sørhaug, Sveinung; Amundsen, Tore; Grønberg, Bjørn Henning; Strasser, Florian; Stephens, Nathan; Hoem, Dag; Molven, Anders; Kaasa, Stein; Fearon, Kenneth; Jacobi, Carsten; Bjørkøy, Geir (Journal article; Peer reviewed, 2017)
      The majority of cancer patients with advanced disease experience weight loss, including loss of lean body mass. Severe weight loss is characteristic for cancer cachexia, a condition that significantly impairs functional ...
    • Cardiovascular mortality ? Comparing risk factor associations within couples and in the total population ? The HUNT Study 

      Bjørngaard, Johan Håkon; Vie, Gunnhild Åberge; Krokstad, Steinar; Janszky, Imre; Romundstad, Pål Richard; Vatten, Lars Johan (Journal article; Peer reviewed, 2017)
      Background To compare associations of conventional risk factors with cardiovascular death within couples and in the population as a whole. Methods We analysed baseline data (1995–97) from the HUNT2 Study in Norway ...
    • Cohort profile: The Nordic Antireflux Surgery Cohort (NordASCo) 

      Maret-Ouda, John; Wahlin, Karl; Artama, Miia; Brusselaers, Nele; Färkkilä, Martti; Lynge, Elsebeth; Mattsson, Fredrik; Pukkala, Eero; Romundstad, Pål Richard; Tryggvadóttir, Laufey; von Euler-Chelpin, My; Lagergren, Jesper (Journal article; Peer reviewed, 2017)
      Purpose To describe a newly created all-Nordic cohort of patients with gastro-oesophageal reflux disease (GORD), entitled the Nordic Antireflux Surgery Cohort (NordASCo), which will be used to compare participants having ...
    • Development and course of chronic pain over 4 years in the general population: The HUNT pain study 

      Landmark, Tormod; Dale, Ola; Romundstad, Pål Richard; Woodhouse, Astrid; Kaasa, Stein; Borchgrevink, Petter Chr. (Journal article; Peer reviewed, 2018)
      Background Epidemiological studies of chronic pain frequently report high prevalence estimates. However, there is little information about the development and natural course of chronic pain. Methods We followed a ...
    • Does pregnancy alter life-course lipid trajectories? Evidence from the HUNT Study in Norway. 

      Markovitz, Amanda Rose; Haug, Eirin Beate; Horn, Julie; Fraser, Abigail; Macdonald-Wallis, Corrie; Tilling, Kate; Rimm, Eric B; Missmer, Stacey A.; Williams, Paige; Romundstad, Pål Richard; Åsvold, Bjørn Olav; Rich-Edwards, Janet Wilson (Journal article; Peer reviewed, 2018)
      We examined the association between pregnancy and life-course lipid trajectories. Linked data from the Nord-Trøndelag Health Study and the Medical Birth Registry of Norway yielded 19,987 parous and 1,625 nulliparous women. ...
    • Does pregnancy complication history improve cardiovascular disease risk prediction? Findings from the HUNT study in Norway. 

      Markovitz, Amanda Rose; Stuart, Jennifer J.; Horn, Julie; Williams, Paige; Rimm, Eric B; Missmer, Stacey A.; Tanz, Lauren J.; Haug, Eirin Beate; Fraser, Abigail; Timpka, Simon; Klykken, Bjørnar E.; Dalen, Håvard; Romundstad, Pål Richard; Rich-Edwards, Janet W.; Åsvold, Bjørn Olav (Journal article; Peer reviewed, 2018)
      To evaluate whether history of pregnancy complications [pre-eclampsia, gestational hypertension, preterm delivery, or small for gestational age (SGA)] improves risk prediction for cardiovascular disease (CVD). Methods and ...
    • Do parental heights influence pregnancy length?: a population-based prospective study, HUNT 2 

      Myklestad, Kirsti; Vatten, Lars Johan; Magnussen, Elisabeth Balstad; Salvesen, Kjell Å; Romundstad, Pål Richard (Journal article; Peer reviewed, 2013-02-05)
      Background: The objective of this study was to examine the association of maternal and paternal height with pregnancy length, and with the risk of pre- and post-term birth. In addition we aimed to study whether cardiovascular ...
    • Duration of the active phase of labor in spontaneous and induced labors 

      Østborg, Tilde Broch; Romundstad, Pål Richard; Eggebø, Torbjørn Moe (Journal article, 2017)
      Introduction The aim of the study was to compare the duration of active phase of labor in women with spontaneous or induced start of labor. Material and methods An observational cohort study was performed at Stavanger ...
    • Early self-reported pain in juvenile idiopathic arthritis (JIA) is related to long-term outcomes. Results from the Nordic JIA cohort study. 

      Arnstad, Ellen Dalen; Rypdal, Veronika Gjertsen; Peltoniemi, Suvi; Herlin, T; Berntson, Lillemor; Fasth, Anders; Nielsen, Susan; Glerup, Mia; Ekelund, Maria; Zak, Marek; Aalto, Kristiina; Nordal, Ellen Berit; Romundstad, Pål Richard; Rygg, Marite (Journal article; Peer reviewed, 2018)
      Objective To study self‐reported pain early in the disease course of juvenile idiopathic arthritis (JIA) as predictor of long‐term disease outcomes. Methods Consecutive cases of JIA with disease onset 1997‐2000 from ...
    • Factors associated with vitamin D deficiency in a Norwegian population: the HUNT Study 

      Larose, Tricia L; Chen, Yue; Camargo, Carlos Arthuro; Langhammer, Arnulf; Romundstad, Pål Richard; Mai, Xiao-Mei (Journal article; Peer reviewed, 2014)
      Vitamin D deficiency occurs worldwide. Winter season and high Body Mass Index (BMI) are associated with low levels of serum 25-hydroxyvitamin D (25(OH)D). We estimated the prevalence of vitamin D deficiency in a Norwegian ...
    • General and abdominal obesity and incident asthma in adults: the HUNT study 

      Brumpton, Ben Michael; Langhammer, Arnulf; Romundstad, Pål Richard; Chen, Yue; Mai, Xiao-Mei (Journal article; Peer reviewed, 2013)
      Measures of body mass index (BMI) and waist circumference define general obesity and abdominal obesity respectively. While high BMI has been established as a risk factor for asthma in adults, waist circumference has seldom ...
    • Health care contact following a new incident neck or low back pain episode in the general population; the HUNT study 

      Woodhouse, Astrid; Pape, Kristine; Romundstad, Pål Richard; Vasseljen, Ottar (Journal article; Peer reviewed, 2016)
      Low back and neck pain are commonly reported in the general population and represent frequent causes for health care consultations. The main aim of this study was to describe the determinants of health care contact during ...
    • Heavier smoking increases coffee consumption: findings from a Mendelian randomization analysis 

      Bjørngaard, Johan Håkon; Nordestgaard, AT; Taylor, Amy E; Treur, Jorien L; Gabrielsen, Maiken Elvestad; Munafo, Marcus R; Nordestgaard, BG; Åsvold, Bjørn Olav; Romundstad, Pål Richard; Davey Smith, George (Journal article; Peer reviewed, 2017)
      Background There is evidence for a positive relationship between cigarette and coffee consumption in smokers. Cigarette smoke increases metabolism of caffeine, so this may represent a causal effect of smoking on caffeine ...
    • Heavier smoking may lead to a relative increase in waist circumference: Evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium 

      Morris, Richard W.; Taylor, Amy E.; Fluharty, Meg E.; Bjørngaard, Johan Håkon; Åsvold, Bjørn Olav; Gabrielsen, Maiken Elvestad; Campbell, Archie; Marioni, Riccardo; Kumari, Meena; Korhonen, Tellervo; Männistö, Satu; Marques-Vidal, Pedro; Kaakinen, Marika; Cavadino, Alana; Postmus, Iris; Husemoen, Lise Lotte N.; Skaaby, Tea; Ahluwalia, Tarun Veer Singh; Treur, Jorien L.; Willemsen, Gonneke; Dale, Caroline; Wannamethee, S. Goya; Lahti, Jari; Palotie, Aarno; Räikkönen, Katri; McConnachie, Alex; Padmanabhan, Sandosh; Wong, Andrew; Dalgård, Christine; Paternoster, Lavinia; Ben-Shlomo, Yoav; Tyrrell, Jessica; Horwood, John; Fergusson, David M.; Kennedy, Martin A.; Nohr, Ellen A.; Christiansen, Lene; Kyvik, Kirsten Ohm; Kuh, Diana; Watt, Graham; Eriksson, Johan G.; Whincup, Peter H.; Vink, Jacqueline M.; Boomsma, Dorret I.; Smith, George Davey; Lawlor, Debbie; Linneberg, Allan; Ford, Ian; Jukema, J. Wouter; Power, Chris; Hyppönen, Elina; Jarvelin, Marjo-Riitta; Preisig, Martin; Borodulin, Katja; Kaprio, Jaakko; Kivimaki, Mika; Smith, Blair H.; Hayward, Caroline; Romundstad, Pål Richard; Sørensen, Thorkild I.A.; Munafo, Marcus R.; Sattar, Naveed (Journal article; Peer reviewed, 2015)
      Objectives: To investigate, using a Mendelian randomisation approach, whether heavier smoking is associated with a range of regional adiposity phenotypes, in particular those related to abdominal adiposity. Design: ...
    • Hypertension in Pregnancy and Offspring Cardiovascular Risk in Young Adulthood: Prospective and Sibling Studies in the HUNT Study (Nord-Trøndelag Health Study) in Norway 

      Alsnes, Ingvild Vatten; Vatten, Lars Johan; Fraser, Abigail; Bjørngaard, Johan Håkon; Rich-Edwards, Janet Wilson; Romundstad, Pål Richard; Åsvold, Bjørn Olav (Journal article; Peer reviewed, 2017)
      Women with hypertensive disorders in pregnancy are at increased lifetime risk for cardiovascular disease. We examined the offspring’s cardiovascular risk profile in young adulthood and their siblings’ cardiovascular risk ...