• Acute and potentially persistent effects of scuba diving on the blood transcriptome of experienced divers 

      Eftedal, Ingrid; Ljubkovic, Marko; Flatberg, Arnar; Jørgensen, Arve; Brubakk, Alf O; Dujic, Zeljko (Journal article; Peer reviewed, 2013)
      During scuba diving, the circulatory system is stressed by an elevated partial pressure of oxygen while the diver is submerged and by decompression-induced gas bubbles on ascent to the surface. This diving-induced stress ...
    • Deadly diving? Physiological and behavioural management of decompression stress in diving mammals 

      Hooker, SK; Fahlman, A; Moore, MJ; de Soto, NA; de Quiros, YB; Brubakk, Alf O; Costa, DP; Costidis, AM; Dennison, S; Falke, KJ; Fernandez, A; Ferrigno, M; Fitz-Clarke, JR; Garner, MM; Houser, DS; Jepson, PD; Ketten, DR; Kvadsheim, Petter Helgevold; Madsen, PT; Pollock, NW; Rotstein, DS; Rowles, TK; Simmons, SE; Van Bonn, W; Weathersby, PK; Weise, MJ; Williams, TM; Tyack, PL (Journal article; Peer reviewed, 2012)
      Decompression sickness (DCS; ‘the bends’) is a disease associated with gas uptake at pressure. The basic pathology and cause are relatively well known to human divers. Breath-hold diving marine mammals were thought to be ...
    • Effects of hyperbaric oxygen preconditioning on cardiac stress markers after simulated diving. 

      Jørgensen, Arve; Foster, Philip P; Brubakk, Alf O; Eftedal, Ingrid (Journal article; Peer reviewed, 2013)
      Hyperbaric oxygen preconditioning (HBO-PC) can protect the heart from injury during subsequent ischemia. The presence of high loads of venous gas emboli (VGE) induced by a rapid ambient pressure reduction on ascent from ...
    • Sidenafil Pre-Treatment Promotes Decompression Sickness in Rats 

      Blatteau, Jean-Eric; Brubakk, Alf O; Gempp, Emmanuel; Castagna, Olivier; Risso, Jean-Jacques; Vallée, Nicolas (Journal article; Peer reviewed, 2013)
      Vascular bubble formation after decompression contributes to endothelial injuries which form the basis for the development of decompression sickness (DCS). Nitric oxide (NO) is a powerful vasodilator that contributes to ...
    • Ultrasound detection of vascular decompression bubbles: The influence of new technology and considerations on bubble load 

      Blogg, Lesley S; Gennser, Mikael; Møllerløkken, Andreas; Brubakk, Alf O (Journal article; Peer reviewed, 2014)
      INTRODUCTION: Diving often causes the formation of 'silent' bubbles upon decompression. If the bubble load is high, then the risk of decompression sickness (DCS) and the number of bubbles that could cross to the arterial ...